• The National Institute of Industrial Property recognized Universidad de Santiago as the second Chilean university at filing the highest number of patent applications in 2014. “Chile has a scientific tradition that places the country at the forefront of the Latin American productivity, and numbers reflect this fact, like the second place reached by Universidad de Santiago (last year).” The award ceremony was held in the context of the World Intellectual Property Day.

Once again, Universidad de Santiago was among the three most outstanding universities in the patent category- a category related to the rights given by the Chilean State to an inventor for the development of a new technology- in the annual award ceremony organized by the National Institute of Industrial Property (Inapi). 

The ceremony was held at Patio Los Naranjos of Universidad de Santiago and it was headed by Katia Trusich, Under Secretary of Economy, Development and Tourism, and Inapi’s NationalDirector, Maximiliano Santa Cruz. The Under Secretary said that last year was a consolidation period for Inapi. And she added that the challenge now is to set out a long-term strategy to allow “the development of industrial property considering the specific requirements of the country with regards to productive development, innovation and business ventures.”

For his part, Inapi’s National Director emphasized that our institution has a very important commitment with regards to patent application processing. “In Chile, universities are doing a good job at patenting and, if they are considered all together, in 2014 they almost doubled the number of patent applications filed, in comparison to the previous year.”

Besides congratulating Universidad de Santiago for its great work and interest in patent matters, she said that our University “is making big efforts to obtain patents, something that should be continued and promoted. Generating new knowledge through scientific activity at universities is an essential tool for economic, social and cultural development.”

“Chile has a scientific tradition that places the country at the forefront of the Latin American productivity, and numbers reflect this fact, like the second place reached by Universidad de Santiago in the national patent application ranking of 2014”, Maximiliano Santa Cruz said.

Luis Magne, Head of the Department of Technology Management of Universidad de Santiago- the unit in charge of processing patent applications of the University, among other tasks- said: “Universidad de Santiago continues to keep its spirit of technological university, so it puts an emphasis on applied research and innovation in order to contribute to the society welfare and to have an impact on Chile and the world.”

According to the information given by the Department of Technology Management, in 2014, Universidad de Santiago filed 23 new patent applications with Inapi, doubling the number of patents filed in 2013. This placed the University in the third position of the ranking that year. In addition, it filed 44 invention and protection patent applications with international agencies.

These patents are related to the fields of Sciences, Engineering, Technology, and Chemistry and Biology, and most of them belong particularly to the areas of Biotechnology, Manufacturing and Aquaculture.

Universidad de Concepción was at the first place in the patent application ranking while Pontificia Universidad Católica was at the third place.

Translated by Marcela Contreras

·         The drugs we use are delivered into our bodies in a short time because they are designed to be adsorbed at the intake and to lose effect some time later. In this field, the first results of a study at Universidad de Santiago are very valuable. The research team looked for an “intelligent” drug-delivery system; i.e. a system for a sustained release of the required dose to increase the drug efficacy. 

To understand the mechanisms that would allow in the future releasing drugs in the best place and at the best time, was one of the goals of the study led by Dr Eduardo Lissi, professor at the Faculty of Chemistry and Biology.

Nowadays, the drugs we use are delivered into our bodies in a short time; i.e., they are designed to be adsorbed at the intake and to lose effect some time later.

The purpose of the study was to understand the factors and cellular processes involved in this type of mechanism and Dr Eduardo Lissi, researcher at Universidad de Santiago, together with the Protein Research Group of the Faculty of Biology of Universidad de la Habana (Cuba) and researchers Alexis Aspee (Universidad de Santiago) and Marco Antonio Soto (Pontificia Universidad Católica de Chile), undertook the project.

“I think this is very interesting: designing “intelligent” systems for a particular effect, placing the carrier in the right place to control there the delivery of the bio-active species,” he says.

He adds that he is very “impressed for the magnitude of the problem and for having the possibility of connecting basic biophysics with its applications, particularly with those related to the potential for elaborating specific drugs especially for a given system.”

According to Dr Lissi, these “intelligent” systems would offer advantages in their application, like designing drugs that are released, “for example, when the host reaches a given temperature and/or a given osmotic gradient.” This would assure a sustained delivery of the dose of the required drug and increase its efficacy.

Another aspect of the study, which is still being worked on, is related to the ability of haemolytic toxins to generate channels that contribute to control cell damage. “This involves and interesting potential to selectively kill cell groups that you want to eradicate,” Dr Lissi says. The name of the project was Fondecyt 1130867, “Studies on the diffusion of small solutes through lipids bilayers in unilamellar liposomes."

Translated by Marcela Contreras

·         In 1859, Charles Darwin published the book “On the Origin of Species”, where he states that invading species with a high degree of evolutionary closeness to the invaded community (phylogenetic relationship), would be less likely to become established, because “struggle for survival” would be more intense between related species. However, experiments conducted by Dr Sergio Castro, researcher at the Faculty of Chemistry and Biology and CEDENNA, have shown something different.

“Many people have accepted Darwin’s hypotheses as incontrovertible facts due to his recognized status in science. However, many of these hypotheses lie on mechanisms that have not been evaluated. This is a common situation in science development: usually the observations made are tested afterwards,” Dr Sergio A. Castro, researcher at the Laboratory of Ecology and Biodiversity of Universidad de Santiago, says.

In order to test Darwin’s hypothesis, Dr Castro and his research team developed a Fondecyt project. In this context, their paper “Evaluating Darwin’s Naturalization Hypothesis in Experimental Plant Assemblages: Phylogenetic Relationships Do Not Determine Colonization Success” was published by the renowned journal PLOS ONE, currently the largest scientific journal in the world, with a high impact factor (Q1) for its citations.

“Different species can be introduced in an area and several of them can finally establish themselves as populations, as if they were native species, without depending on human action. These are considered naturalized species. In our experiment, we observed a colonizing plant in different vegetal communities. These communities had different degrees of phylogenetic relatedness with the invading species. If Darwin was right, a trend towards the establishment of the invading species would have been recorded, depending on the evolutionary relatedness. However, after three years, we evaluated the results and they did not support Darwin’s hypothesis,” Dr Castro says.

The experiment was conducted in Batuco (a place close to Santiago) and 15 species were selected. One of them, the native lettuce Lactuca, was used as a colonizing or invading species, while the other 14, like chamomile, broad bean, arugula, among others, were used as experimental assemblage communities. With these plants, five treatments were organized according to their different phylogenetic relatedness with respect to Lactuca. They showed that colonization did not depend on phylogenetic relatedness. 

“En nuestro estudio todas las plantas pudieron convivir, independiente de sus parentescos. Por esto, los resultados manifiestan que la hipótesis de Darwin no tiene un respaldo tan sólido o por lo menos no es tan general como él lo planteaba”, indica Castro.

“In our study, all plants were able to coexist, regardless of their relatedness. Therefore, the results show that Darwin’s hypothesis does not have a strong base or, at least, the hypothesis is not as generalized as he stated,” Dr Castro says.

The researcher has also evaluated Darwin’s naturalization hypothesis by analyzing the composition of Chilean flora and introduced exotic plants. This work not only disproved the hypothesis, but it yielded opposite results.

“We found that species from other environments can be introduced in Chile’s central zone and find relatives that survive well in this climate. These relatives can provide pollinators and seed dispersers, making naturalization more likely to happen, contrary to what is expected in Darwin’s hypothesis,” he says.

Having an impact on global change

In the past few decades, people have become more interested in knowing how the different human activities affect the environment. The focal point has been climate change, passing over other factors, like introducing foreign species, flora or fauna, in other places. These factors are considered as part of global change.

“Chile is a biogeographic island. It is surrounded by a mountain chain, a desert and an ocean; therefore its flora has evolved isolated for more than 180 years. However, in the past centuries some species have been introduced that are risky to native species,” he explains.

Chile’s central zone biogeography is so particular that it is considered one of the 35 biodiversity hotspots of the world. These places are characterized by a high level of species endemism, but at the same time, their preservation is in danger as a result of human impact.

“An introduced species can produce the extinction of a native one, damaging our biodiversity. Nowadays, our variety of exotic plants is wide if compared with the variety of our native flora. But, what can we do to prevent this situation? There is little we can do in a globalization context, but we can generate diagnosis to prevent some species from entering and becoming naturalized,” Dr Castro says.

Translated by Marcela Contreras

• Researchers at the Faculty of Chemistry and Biology of Universidad de Santiago discovered the existence of functional TRP ion channels in the marine alga Ulva Compressa that are similar to the ones present at the nervous system in mammals and humans. “At first, it was difficult to imagine that these channels could exist in a marine alga, especially when they exist in mammals but not in terrestrial plants,” Dr Alejandra Moenne, researcher at the Department of Biology, says.

TRP channels are cellular sensors that detect and respond to different environmental stimuli, like temperature changes, pain and taste, what makes them key to many physiological processes.

“At first, it was difficult to imagine that these channels could exist in a marine alga, especially when they exist in mammals but not in terrestrial plants,” Dr Alejandra Moenne, researcher at the Department of Biology, says.

“Before having these results, we found that copper stress activates voltage dependent calcium channels (VDCC) similar to the ones present at the central nervous system of mammals. So, how the activation of voltage dependent channels was possible? We thought that the activation of VDCC depended on the previous activation of TRP channels, something difficult to imagine in a marine alga,” the researcher explains.

These results mean a change in the way how the physiological functioning of marine algae - organisms that have been present on Earth for about a thousand million years- is understood. They were published by the journal Frontiers in Plant Science in the paper "Copper-induced activation of TRP channels promotes extra cellular calcium entry, activation of CaMs and CDPKs, copper entry and membrane depolarization in Ulva compressa.” 

The researcher explains that they not only found that “there are functional TRP channels that respond to copper but also that copper stress induces the release of amino acids and amino acid derived neurotransmitters similar to the ones released by human neurons. Even more, we have preliminary evidence that suggests that there is communication among different marine algae species through these molecules.”


Future research 

In terms of research and to give answers to the new questions, Dr Moenne says that she intends to apply for a Proyecto Anillo together with researchers Juan Pablo García-Huidobro (Universidad de Santiago), Claudio Sáez (Universidad de Playa Ancha) and Erasmo Macaya (Universidad de Concepción), in order to deepen the knowledge on the communication among green, red and brown marine algae.

“As algae release amino acids and neurotransmitters- and have TRP channels and voltage dependent channels- algae functioning would be more and more similar to neurons, but with a slower response in minutes or hours, instead of the milliseconds of the neurons response,” she explains.

The paper "Copper-induced activation of TRP channels promotes extra cellular calcium entry, activation of CaMs and CDPKs, copper entry and membrane depolarization in Ulva compressa" (that received the recognition of the Editor of the journal Frontiers in Planet Science) was written by the research team of this project: Melissa Gómez, Alberto González, Claudio Sáez, Bernardo Morales and Alejandra Moenne. It is available online at http://journal.frontiersin.org/article/10.3389/fpls.2015.00182/abstract 


Translated by Marcela Contreras

• The Regular Fondecyt Project “Mapping underlying genetic variants in nitrogen assimilation in different natural yeasts” led by Dr Claudio Martínez, researcher at the Food Science and Technology Research Center of Universidad de Santiago, proposes a new wine fermentation method that will not depend on nitrogen levels in the must. The study will last until 2019 and it involves the participation of researchers at the Department of Food Science and Technology of Universidad de Santiago and foreign experts from the CNRS in Nice (France) and the Instituto de Agroquímica y Tecnología de Alimentos in Valencia (Spain).

​

Yeasts are essential for wine fermentation as they turn grape sugar into alcohol. However, current industrial yeasts do not guarantee the completion of the fermentation process, resulting in economic losses for the national wine-making industry.

“It is estimated that about 40 per cent of the fermentation processes are interrupted, with a very strong impact on the industry. If you interrupt the process, thousands of litres will not ferment, so you need to spend more money to complete the process by adding more yeast or nutrients. This affects the wine properties and the quality expected,” Dr Claudio Martínez, director of the Food Science and Technology Research Center of Universidad de Santiago (Cecta, in Spanish), said.

To solve this problem, Dr Martínez and researchers at Universidad de Santiago are currently conducting the Regular Fondecyt Project “Mapping underlying genetic variants in nitrogen assimilation in different natural yeasts,” that will last until 2019.

“For yeasts to develop and work well, the abundant presence of some nutrients, like nitrogen, is required. As some musts have low levels of nitrogen, yeasts there do not grow well and the resulting product is not good. We will study the genes of Chilean native yeasts and foreign yeasts, searching for the ones that allow the yeast to assimilate nitrogen without considering its levels, and ferment the must efficiently,” he explained.

The yeasts described have been collected by the researchers at Cecta during the past decade, what allowed obtaining the most complete yeast strain collection of the country. With this register and through a previous Fondef Project, the Cecta developed a yeast strain, Fermicru XL, which has already been patented and commercialized worldwide.

“This new study has the purpose of identifying the genes with the features previously described to genetically improve industrial yeasts, something that has not been done before in Chile. First, we will search for the genes with the features we want in native yeasts and then, we will enhance an industrial strain, without using transgenic techniques,” he said.

The project will have the collaboration of Dr Amparo Querol of the Instituto de Agroquímica y Tecnología de Alimentos (IATA), in Valencia, Spain and Dr Gianni Liti, of the National Center for Scientific Research, (CNRS, in French), in Nice, France. Both centers will work on the genetic enhancement of yeast and the development of procedures for genetic investigation. Besides, they will allow access to their own collections of yeast native strains.

“They have yeast strains that they have collected from all over the world, representing more than 70 per cent of the world’s genetic varieties of yeasts. This is a very important genetic source that we will have available when conducting our study,” he added.

Dr Angélica Ganga, professor at the Department of Food Science and Technology; Dr Francisco Cubillos, researcher at Cecta; Dr Álvaro Díaz, of Universidad Católica de Valparaíso; and Dr Cristián Araneda, of Universidad de Chile, will also be part of the research team.

“It is important to study native yeasts. We assume that they have adapted to some environmental factors, so their properties can be potential solutions for the industry. This opportunity to study them allows us to progress in solving some issues, to develop genetic enhancement, and if everything goes as expected, to patent future yeasts based on native strains of our country,” Dr Martínez concluded.

Translated by Marcela Contreras

• “Entre biología y Utopía: Semblantes Ideológicos en las Ciencias de la Vida’ is the name of the Fondecyt Initiation project led by Dr Mauricio Espósito that will allow a synergy between biomedical research, communications and their future interactions. The study will last two years and it expects to prove the importance of the relations among different disciplines.

To analyze the historical and philosophical relation between biological knowledge and its multiple political, ideological and technocratic applications: that is the goal of the Fondecyt Initiation project led by Dr Maurizio Espósito. For this purpose, the academic at the Department of Philosophy of Universidad de Santiago will review some particular cases associated to sciences of life during the 20^th and the 21^st centuries, like the development of genomics in Latin America, for example.

Dr Espósito thinks that “it is very important to understand the philosophical and political implications of biomedical research beyond preconceived criticism, superficial exaltation of science or a merely abstract debate about what is right or wrong.”

According to him, some biological disciplines were formulated since ambitious scientific policies, which principles still cross with biotechnological utopias and contemporary ideologies.

“I think that many people speak about biotechnology or technology often criticizing or glorifying technological or scientific events without really understanding them. And understanding them does not only mean knowing the technical details unique to a discipline, but also having a definite idea about the controversies, interests, concepts, institutions and ambitions of the agents under the great umbrella that we call techno-science, that involves an interdisciplinary approach,” he says.

General guidelines

In this Fondecyt Initiation project, the academic expands his research line to address different national and Latin American cases. “I need to make clear that in this project, I am not interested in criticizing scientific events or proposing philosophical morals based on science-fiction fantasies. The project seeks to link up biotechnological research with the help of the history of science and the interdisciplinary tools given by the studies on science, technology and society,” he adds.

Among the possible options to spread the project information, Dr Espósito recognizes the value of the potential debate among the different disciplines of study and he adds that different activities will be organized, in which academics and the community in general will be able to participate, discuss and think about this issues.

Translated by Marcela Contreras

• A plastic bag takes 1,000 years to break down. In light of this situation, biodegradable materials have become a good option. This is the context in which the study led by Dr Ana Carolina López Dicastillo, a member of the Center for the Development of Nanoscience and Nanotechnology of Universidad de Santiago, is being conducted. Thanks to the electrospinning technique, her research team will produce nanoparticles able to enhance the properties of biodegradable materials in order to obtain, in the long term, more eco-friendly packaging.

It is widely known that a plastic bag takes 1,000 years to break down, causing harm to the environment. Biodegradable materials are an alternative to solve this problem, because they are highly beneficial to the environment when they are adequately discarded. However, these materials do not have the same barrier and mechanical properties that petroleum-based products do, so they become fragile and highly permeable.

Thanks to the electrospinning technique, the research team will produce nanoparticles able to enhance the properties of biodegradable materials in order to obtain, in the long term, more eco-friendly packaging. The study is led by Dr Ana Carolina López Dicastillo, a member of the Center for the Development of Nanoscience and Nanotechnology of Universidad de Santiago, (Cedenna, in Spanish).

This Regular Fondecyt project, which is in its second year, seeks to improve the properties of a biodegradable material by incorporating nanoparticles produced by electrospinning to eventually use this material for food packaging. The electrospinning technique has not been frequently used in our country.

The electrospinning process allows obtaining fiber by means of the coaxial stretching of a viscoelastic solution. The diameter of the electrospun fibers ranges from microns no nanometers and they may have unique features.

Due to its interesting properties, this technique has been widely studied in the past few years for a wide variety of applications, like tissue engineering, the creation of special membranes and medical applications like dental implants and bone replacement. In this case, the project is oriented to enhance the properties of biodegradable materials for food industry applications. “Besides developing and working with nanoparticles and nanofibers, this technique allows encapsulating active compounds for their further release, what is also important in the food industry,” Dr López said.

The study seeks to enhance the essential properties of a biodegradable polymer and to create a biodegradable packaging with antioxidant and antimicrobial properties to protect food and to extend its shelf life.

Dr. López Dicastillo, who is responsible for the study, explains that “one of the expectations that we have with this work is trying to implement the concept of reducing plastic products in daily life, replacing traditional materials with biodegradable ones and the awareness of recycling and sustainability.”

She has the goal of making people aware of the problem posed by the plastic waste buildup and the need for replacing petroleum-based products with biodegradable materials, as petroleum is not a renewable resource.

“However, these (biodegradable) materials do not have the properties that the market demands yet. This is why we propose to enhance them and one of the solutions to this problem is nanotechnology. In our project, we are developing a type of nanoparticle that can make biodegradable materials properties to be similar to the ones of traditional plastic products in the market,” she said.

“We also intend to disseminate this study at different levels: from teaching children the importance of these existing biodegradable materials, emphasizing the need for recycling, to scientific conferences and presentations,” the researcher concluded.

Translated by Marcela Contreras

• Researchers at the Food Science and Technology Research Center of Universidad de Santiago de Chile (CECTA- USACH, its acronym in Spanish) will participate in a Fondef project that seeks to improve enzymes’ ability to produce lactose-free milk in cold conditions, increasing the efficacy of the dairy products industry. In partnership with members of the Chilean Antarctic Institute (INACH, its acronym in Spanish), they will search for enzymes in different microorganisms from the Antarctica that would allow working at low temperatures. In Chile, 60% of the population suffers from lactose intolerance.

 

Lactose intolerance is a condition that affects millions of people all over the world. It is estimated that 30 to 50 million people in the United States suffer, to some degree, from this condition. An estimated 90% of the Asian population has the same problem, just like 60% of the Chilean population.

Lactose is a type of sugar found in milk and other dairy products. The body needs an enzyme called lactase to break down lactose. Lactose intolerance occurs when the small intestine cannot produce enough lactase. This is the reason why lactose content in milk has to be reduced, so that people suffering from this condition are able to drink it.

The project expects to detect an enzyme that allows breaking down lactose at low temperatures and at a better level of efficiency than the one of the enzyme currently used in the industry. Researchers will search for this enzyme in different microorganisms (fungi, yeasts and bacteria) that have been already isolated and brought from the Antarctic continent.

Once the efficacy at low temperatures of this “Antarctic enzyme” is described and tested, the project will be able to move forward to obtain the resources required for creating the conditions to transfer this biotechnological product to the industry.

In this way, finding enzymes which are highly effective in reducing the lactose content of milk at low temperatures will not only allow to optimize some of the current production processes, but it will also open new possibilities for the design of lactose-content reducing processes in cold conditions and for the production of lactose-free foods.

The project called “Antarctic enzyme with highly effective β-galactosidase activity to reduce lactose content of milk at low temperatures” (ID14I10098) will last for two years and will be funded by Fondef and Universidad de Santiago. It will be led by Dr Renato Chávez Rosales (Director), professor at the Faculty of Chemistry and Biology of Universidad de Santiago de Chile, and Dr José Luis Palacios Pino (Alternate Director), researcher at Cecta-Usach.

The experts will work in partnership with members of the Chilean Antarctic Institute in the search for the enzyme in different microorganisms brought from the Antarctica.

Translated by Marcela Contreras

• Cyanide is one of the most commonly used chemicals in gold mining, mainly because it is easy to obtain and is highly effective in recovering this metal. However, due to its high levels of toxicity, its use should be controlled to avoid leaks. This is the reason why the process suggested in the study led by Dr Julio Romero, professor at the Department of Chemical Engineering of our University, is so important.

 

“These processes require very large equipment and a constant control, and may involve potential hazards, like leaks. This fact is particularly critical, because there may be gas streams containing cyanide as hydrogen cyanide flowing in the plant through large columns that could affect both people and the environment, if they are not handled with enough caution,” Dr. Julio Romero, researcher at the Department of Chemical Engineering, said.

For these reasons and according to the research lines of the Laboratory of Membrane Separation Processes (LabProSeM) of Universidad de Santiago de Chile, the research team conducted a study to minimize the risk posed by the changing conditions of cyanide by means of a membrane absorption process. The study was published by the Journal of Membrane Science with the name of “Design and cost estimation of a gas-filled membrane absorption (GFMA) process as alternative for cyanide recovery in gold mining.”

“We developed and adapted a new process that requires only one confined and compact piece of equipment. It allows cyanide to pass from one phase to the other without having to change its condition to gaseous state in a circulating stream, thanks to a membrane that absorbs and desorbs this substance in one stage,” he explained. 

The system works as a selective barrier, partly similar to biological membranes. These membranes are commercialized in the market and they are adapted for this specific use.

“This time, we evaluated a membrane with gas-filled pores, specifically, air-filled pores. In this way, the two solutions- the one from which the cyanide will be removed and the one in which the cyanide will be kept- contact each other passing through the membrane pores. This allows a controlled operation, reducing the risk of cyanide escapes into the atmosphere,” Dr Romero said.

The study was developed as of some systems that simulated the composition of the water in a gold deposit. This increases the feasibility of the design in real operations, because it suggests a reduction in the energy footprint of the process. Besides, it produces a 35% more of the net value provided by the AVR system and is comparable to the SART process.

The published article is the result of a more extensive study related to the dissertation work of Humberto Estay, graduated from the Engineering Sciences PhD program with a Major in Process Engineering, at Universidad de Santiago. Students and academics at Universidad Tecnológica Metropolitana have also contributed to this work.

Contributing to Green Chemistry

The LabProSeM has worked for more than 14 years on the study of membrane separation processes and their use in hydrometallurgical processes, food processing, biofuel separation and gas and waste management.  

Currently, the different studies supported by this laboratory have an ultimate goal: to incorporate the principles of eco-friendly chemistry. This idea was inspired by the green chemistry philosophy, based on 12 principles that intend to reduce the impact of future chemical processes.

“Membranes, as selective barriers, use a physical means to restrict the use of reagents and chemicals harmful to the environment. We would like to focus our research lines on the development of applications that respect the principles of green chemistry. We try to modify the design of our products, chemical treatments, processes and others, to make them eco-friendly. All this with the purpose of eliminating or considerably reducing the production of pollutants,” Dr Romero said.

Translated by Marcela Contreras

• Yeast is a type of fungus that is present in multiple fermentation processes required for food. Due to this fact, new applications of yeast are being studied to decontaminate what we eat in a natural way and at low costs. The study is being conducted in the context of an Initiation Fondecyt project led by Dr Francisco Cubillos Riffo, a researcher at the Food Science and Technology Research Center of Universidad de Santiago.
  
   
  
  Yeast plays an essential role in the making of liquors, beer and bread. This fungus allows multiple fermentation processes required for producing foods as we know them. However, the importance of this catalyst goes beyond food production: it has the characteristic of controlling some mycotoxins. Mycotoxins are natural food contaminants that can cause acute poisoning when ingested, inhaled or absorbed.
  
  Through a genetic analysis of the response to the interaction between natural contaminants and yeast, the study led by Dr Francisco Cubillos Riffo seeks to develop new applications that allow decontaminating foods in a natural way and at low costs. 
  
  According to professor Cubillos, food innocuousness is very important in Chile, both for imports and exports. “The laboratory of Food Science and Technology Research Center of Universidad de Santiago (CECTA) is focused on research on food innocuousness. The type of yeast that we are studying now has the characteristic of decontaminating mycotoxin-containing foods,” he added.
  
  Preventing diseases
  
  The importance of this study lies on the need for preventing diseases transmitted by animals, eliminating contamination of human-consumption products. The analysis of this strain and others coming from different places in the country seems to be suitable to find effective applications.
  
  “We will study yeasts of different origins and then we will evaluate them at a genetic level. We will be able to determine what yeast is the one with the highest ability to degrade pollutants or decontaminate food, and at the same time, will conduct genetic studies on the different strains collected,” Dr Cubillos said.
  
  “Many of these toxins manage to enter the food chain and cause damage; therefore, it is necessary to find natural alternatives for decontamination. Yeast is not a chemical product, it is not a toxic treatment, it is cheaper, and most of the time, it is completely innocuous,” he added.
  
  The study will have a broad impact and Dr Cubillos considers the new possibilities as favorable. “Eventually, we could reach the industry and start partnerships with the Faculty of Administration and Economics. Also, with the data collected during the project, mathematical models can be developed to determine the specific behavior of yeasts in stressful environments, what would contribute even more to future studies,” he said.
  
  Translated by Marcela Contreras